Several years ago, after smoking 30mg. of 5-MeO (or that should be after a month or so of trying to make sense from smoking it) I starting exploring the insufflation route. Measurements were crude, but moderately accurate. Dosage, I don't think, ever went over 5mg. It was usually around 1-3mg. This dosage produced very strange effects -- although not as intense as smoking. As you mentioned, the coming on was very slow compared to smoking...I would snort some and then sit down...wait a few minutes, my nostils would begin to feel like cement had been poured into them, my teeth seemed to hurt, and yeah, basic burning...you could see and feel the effects arising. This route is definitely a way to feel out the coming on of 5-MeO. However, the experiences at these low doses ranged immensely. Several times, I snorted a small helping and once it effected me, I became intensely tired and feel asleep. However, more often I would take the dosage and in the intoxication become extremely stimulated and excited! There was little predictability other than the lack of visuals and the possible recreational feel to it. I did one small cannister of nitrous oxide when I was coming on (one of the times I was feeling the stimulation rising up my spine) and I fell into the wall. Nitrous in this dose has never knocked me out for even a moment. In small doses, the burn wasn't nearly as bad as snorting 2-CB (which is the closest approximation I can surmise as to the punishment HELL would bring), but the dosage was much less than is needed with beez. I also did feel the cooling of my body, even in the time when I would become stimulated. Of course, this easy route of administration did have a down side (other than the burning) for my personality. With the quantity obtained, I ended up insufflating 5-MeO (or occasionally smoking it) almost daily for a month or so. No side effects were noted at that time. But then my supply ran out and I did not intend to get more...my personality was smashed. I began to suffer panic attacks and could not stand being in public places...and my mind seemed to be retreating on me. I had difficulty seeing myself as a single entity and there was a definite increase in chatter and voices within my head. These side-effects lasted for at least 2 months after I stopped using 5-MeO. They were most maddening. -Rev. MeO